What two agencies manage the Select Agent Program?

• A. National Institutes of Health and Centers for Disease Control and Prevention
• B. Environmental Protection Agency and Department of Transportation
• C. Federal Bureau of Investigation and Central Intelligence Agency
• D. Division of Select Agents and Toxins (CDC, part of HHS) and Agriculture Select Agent Services (APHIS, USDA)

Answer: (D)

The program is a joint effort between the Department of Health and Human Services and the Department of Agriculture. It is run by two units: the Division of Select Agents and Toxins within the CDC (HHS) and the Agriculture Select Agent Services within APHIS (USDA). This dual oversight reflects that select agents include those affecting human health as well as those affecting animal and plant health and agriculture, requiring coordinated federal regulation, registration, and security controls.