What action did the FDA take in 2005 regarding enrofloxacin in poultry?

• A. Expanded its uses
• B. Kept approval unchanged
• C. Withdrawn approval
• D. Moved approval to other species

Answer: (C)

Regulatory actions on antimicrobials in food-producing animals are driven by protecting human health from resistance. Enrofloxacin is a fluoroquinolone used in poultry, and by the early 2000s it was clear that using such drugs in birds could promote fluoroquinolone-resistant bacteria that threaten people who might become infected. To address this risk, the FDA withdrew approval for enrofloxacin in poultry in 2005, removing the legal use of the drug in chickens and turkeys. This preserves the effectiveness of important antimicrobials for human medicine and reduces resistance risk in poultry.