In regards to live animal vaccines, which agency licenses animal vaccines and which agency looks for vaccine reactions at slaughter?

• A. Licenses: FDA; Reactions: APHIS
• B. Licenses: APHIS; Reactions: FSIS
• C. Licenses: FSIS; Reactions: APHIS
• D. Licenses: CDC; Reactions: FSIS

Answer: (B)

Licensing of live animal vaccines is handled by APHIS, specifically the Center for Veterinary Biologics, which reviews safety, efficacy, and manufacturing quality and then licenses veterinary biologics for use in animals. The agency that monitors for adverse vaccine reactions at slaughter is FSIS, the Food Safety and Inspection Service, which conducts postmortem inspections and surveillance to detect issues in carcasses, including reactions linked to prior vaccination. This division of labor matches APHIS’s role in approving veterinary biologics with FSIS’s role in meat safety surveillance at slaughter.