Development of HFRS associated with Seoul virus occurs in more than 60% of cases.

• A. True
• B. False - rare
• C. Not sure
• D. It depends on exposure

Answer: (B)

Seoul virus infections often produce mild illness or subclinical cases, and when HFRS does occur, it tends to be milder with a low mortality rate. Because the majority of infections do not progress to clinical HFRS, the idea that development occurs in more than 60% of cases overstates the risk. In practice, progression to HFRS from Seoul virus exposure is relatively uncommon, hence the statement is false and the outcome is better described as rare.